| Item Type | Name |
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Academic Article
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Lovastatin inhibits T-cell proliferation while preserving the cytolytic function of EBV, CMV, and MART-1-specific CTLs.
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Concept
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Antigen Presentation
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Concept
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HLA-A1 Antigen
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Concept
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Receptors, Antigen
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Concept
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Receptors, Antigen, T-Cell, alpha-beta
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Concept
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Receptors, Antigen, T-Cell
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Concept
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T-Cell Antigen Receptor Specificity
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Concept
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Lymphocyte Function-Associated Antigen-1
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Concept
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Macrophage-1 Antigen
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Concept
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Histocompatibility Antigens Class II
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Concept
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Antigen-Presenting Cells
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Concept
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B7-1 Antigen
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Concept
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CD11c Antigen
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Concept
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B7-2 Antigen
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Concept
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HLA-A2 Antigen
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Concept
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CD146 Antigen
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Academic Article
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HLA-A0201 positive pancreatic cell lines: new findings and discrepancies.
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Academic Article
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Altered decamer and nonamer from an HLA-A0201-restricted epitope of Survivin differentially stimulate T-cell responses in different individuals.
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Academic Article
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Plasmacytoid dendritic cells induce NK cell-dependent, tumor antigen-specific T cell cross-priming and tumor regression in mice.
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Academic Article
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Costimulation enhances the active immunotherapy effect of recombinant anticancer vaccines.
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Academic Article
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Recognition of human colon cancer by T cells transduced with a chimeric receptor gene.
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Academic Article
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Human dendritic cells require multiple activation signals for the efficient generation of tumor antigen-specific T lymphocytes.
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Academic Article
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A phase I study of nonmyeloablative chemotherapy and adoptive transfer of autologous tumor antigen-specific T lymphocytes in patients with metastatic melanoma.
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Academic Article
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Recombinant fowlpox viruses encoding the anchor-modified gp100 melanoma antigen can generate antitumor immune responses in patients with metastatic melanoma.
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Academic Article
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Correspondence re R. Lapointe et al., CD40-stimulated B lymphocytes pulsed with tumor antigens are effective antigen-presenting cells that can generate specific T cells. Cancer Res 2003;63:2836-43.
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Academic Article
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Presentation of tumor antigens by dendritic cells genetically modified with viral and nonviral vectors.
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Academic Article
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BRAF inhibition is associated with enhanced melanoma antigen expression and a more favorable tumor microenvironment in patients with metastatic melanoma.
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Academic Article
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Minicircle DNA is superior to plasmid DNA in eliciting antigen-specific CD8+ T-cell responses.
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Academic Article
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In vivo antitumor activity of T cells redirected with chimeric antibody/T-cell receptor genes.
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Academic Article
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Dendritic cells retrovirally transduced with a model antigen gene are therapeutically effective against established pulmonary metastases.
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Academic Article
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Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma.
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Academic Article
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Impact of cytokine administration on the generation of antitumor reactivity in patients with metastatic melanoma receiving a peptide vaccine.
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Academic Article
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Efficient gene transfer to human peripheral blood monocyte-derived dendritic cells using human immunodeficiency virus type 1-based lentiviral vectors.
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Academic Article
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Cell transfer therapy for cancer: lessons from sequential treatments of a patient with metastatic melanoma.
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Academic Article
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Dendritic cells strongly boost the antitumor activity of adoptively transferred T cells in vivo.
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Academic Article
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Intralymphatic dendritic cell vaccination induces tumor antigen-specific, skin-homing T lymphocytes.
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Academic Article
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Plasmacytoid dendritic cells synergize with myeloid dendritic cells in the induction of antigen-specific antitumor immune responses.
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Academic Article
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TGF-beta1 induces preferential rapid expansion and persistence of tumor antigen-specific CD8+ T cells for adoptive immunotherapy.
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Academic Article
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2E8 binds to the high affinity I-domain in a metal ion-dependent manner: a second generation monoclonal antibody selectively targeting activated LFA-1.
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Academic Article
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Immunotherapy of melanoma: an update.
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Academic Article
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Induction of TLR4-dependent CD8+ T cell immunity by murine ?-defensin2 fusion protein vaccines.
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Academic Article
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Radiologic manifestations of immune-related adverse events in patients with metastatic melanoma undergoing anti-CTLA-4 antibody therapy.
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Academic Article
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Broad cross-presentation of the hematopoietically derived PR1 antigen on solid tumors leads to susceptibility to PR1-targeted immunotherapy.
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Academic Article
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Persistent antigen at vaccination sites induces tumor-specific CD8? T cell sequestration, dysfunction and deletion.
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Academic Article
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Chemical castration of melanoma patients does not increase the frequency of tumor-specific CD4 and CD8 T cells after peptide vaccination.
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Academic Article
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Interleukin-2-transduced lymphocytes grow in an autocrine fashion and remain responsive to antigen.
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Academic Article
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The genetic modification of T cells for cancer therapy: an overview of laboratory and clinical trials.
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Academic Article
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Retroviral transduction of human dendritic cells with a tumor-associated antigen gene.
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Academic Article
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A T cell-independent antitumor response in mice with bone marrow cells retrovirally transduced with an antibody/Fc-gamma chain chimeric receptor gene recognizing a human ovarian cancer antigen.
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Academic Article
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Unopposed production of granulocyte-macrophage colony-stimulating factor by tumors inhibits CD8+ T cell responses by dysregulating antigen-presenting cell maturation.
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Academic Article
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CD40 ligand and lipopolysaccharide enhance the in vitro generation of melanoma-reactive T-cells.
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Academic Article
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CD40-stimulated B lymphocytes pulsed with tumor antigens are effective antigen-presenting cells that can generate specific T cells.
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Academic Article
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Inability to immunize patients with metastatic melanoma using plasmid DNA encoding the gp100 melanoma-melanocyte antigen.
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Academic Article
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Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma.
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Academic Article
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Immunization against MUC18/MCAM, a novel antigen that drives melanoma invasion and metastasis.
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Academic Article
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Treating cancer by targeting the immune system.
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Academic Article
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Detection and characterization of a novel subset of CD8?CD57? T cells in metastatic melanoma with an incompletely differentiated phenotype.
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Academic Article
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Agonistic antibody to CD40 boosts the antitumor activity of adoptively transferred T cells in vivo.
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Academic Article
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A new approach to simultaneously quantify both TCR a- and ?-chain diversity after adoptive immunotherapy.
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Academic Article
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Antagonist antibodies to PD-1 and B7-H1 (PD-L1) in the treatment of advanced human cancer--letter.
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Academic Article
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Immunizing patients with metastatic melanoma using recombinant adenoviruses encoding MART-1 or gp100 melanoma antigens.
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Academic Article
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Adoptive transfer of cloned melanoma-reactive T lymphocytes for the treatment of patients with metastatic melanoma.
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Academic Article
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Mobilization of dendritic cell precursors in patients with cancer by flt3 ligand allows the generation of higher yields of cultured dendritic cells.
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Academic Article
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Expression of a "self-"antigen by human tumor cells enhances tumor antigen-specific CD4(+) T-cell function.
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Academic Article
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Immunization of patients with metastatic melanoma using both class I- and class II-restricted peptides from melanoma-associated antigens.
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Academic Article
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A novel strategy for rapid and efficient isolation of human tumor-specific CD4(+) and CD8(+) T-cell clones.
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Academic Article
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MART-1-specific melanoma tumor-infiltrating lymphocytes maintaining CD28 expression have improved survival and expansion capability following antigenic restimulation in vitro.
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Academic Article
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The ubiquitin ligase Peli1 negatively regulates T cell activation and prevents autoimmunity.
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Academic Article
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Efficient transfer of a tumor antigen-reactive TCR to human peripheral blood lymphocytes confers anti-tumor reactivity.
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Academic Article
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PD-L1 expression in triple-negative breast cancer.
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Academic Article
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IL-2 therapy promotes suppressive ICOS+ Treg expansion in melanoma patients.
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Academic Article
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Effective innate and adaptive antimelanoma immunity through localized TLR7/8 activation.
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Academic Article
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Activation and propagation of tumor-infiltrating lymphocytes on clinical-grade designer artificial antigen-presenting cells for adoptive immunotherapy of melanoma.
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Academic Article
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BRAFV600E Co-opts a Conserved MHC Class I Internalization Pathway to Diminish Antigen Presentation and CD8+ T-cell Recognition of Melanoma.
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Academic Article
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CCR 20th Anniversary Commentary: Chimeric Antigen Receptors-From Model T to the Tesla.
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Academic Article
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STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunity.
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Academic Article
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Loss of PTEN Promotes Resistance to T Cell-Mediated Immunotherapy.
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Academic Article
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T cells and T cell tumors efficiently generate antigen-specific cytotoxic T cell immunity when modified with an NKT ligand
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Academic Article
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BRAFV600E co-opts a conserved MHC class I internalization pathway to diminish antigen presentation and CD8+ T-cell recognition of melanoma
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Academic Article
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Intratumoral CD40 activation and checkpoint blockade induces T cell-mediated eradication of melanoma in the brain.
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Academic Article
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T cells and T cell tumors efficiently generate antigen-specific cytotoxic T cell immunity when modified with an NKT ligand.
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Academic Article
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Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade.
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Academic Article
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Clinical, Molecular, and Immune Analysis of Dabrafenib-Trametinib Combination Treatment for BRAF Inhibitor-Refractory Metastatic Melanoma: A Phase 2 Clinical Trial.
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Academic Article
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Loss of IFN-? Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy.
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Academic Article
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CpG-based immunotherapy impairs antitumor activity of BRAF inhibitors in a B-cell-dependent manner.
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Academic Article
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Novel algorithmic approach predicts tumor mutation load and correlates with immunotherapy clinical outcomes using a defined gene mutation set.
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Academic Article
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Radiation necrosis with stereotactic radiosurgery combined with CTLA-4 blockade and PD-1 inhibition for treatment of intracranial disease in metastatic melanoma.
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Academic Article
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Integrated molecular analysis of tumor biopsies on sequential CTLA-4 and PD-1 blockade reveals markers of response and resistance.
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Academic Article
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Chimeric antigen receptor T-cell therapy - assessment and management of toxicities.
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Academic Article
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Stereotactic radiosurgery of early melanoma brain metastases after initiation of anti-CTLA-4 treatment is associated with improved intracranial control.
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Academic Article
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SLC45A2: A Melanoma Antigen with High Tumor Selectivity and Reduced Potential for Autoimmune Toxicity.
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Academic Article
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Multifaceted Role of BTLA in the Control of CD8+ T-cell Fate after Antigen Encounter.
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Academic Article
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Prospective Analysis of Adoptive TIL Therapy in Patients with Metastatic Melanoma: Response, Impact of Anti-CTLA4, and Biomarkers to Predict Clinical Outcome.
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Academic Article
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Toxicity management after chimeric antigen receptor T cell therapy: one size does not fit 'ALL'.
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Academic Article
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RNA editing derived epitopes function as cancer antigens to elicit immune responses.
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Concept
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gp100 Melanoma Antigen
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Concept
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MART-1 Antigen
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Concept
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HLA-A24 Antigen
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Concept
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B7-H1 Antigen
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Concept
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CTLA-4 Antigen
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Academic Article
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Atezolizumab plus cobimetinib and vemurafenib in BRAF-mutated melanoma patients.
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Academic Article
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Immuno-genomic landscape of osteosarcoma.
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Academic Article
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18F-fluorodeoxyglucose positron emission tomography correlates with tumor immunometabolic phenotypes in resected lung cancer.
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Academic Article
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Perspectives in melanoma: meeting report from the "Melanoma Bridge" (December 5th-7th, 2019, Naples, Italy).
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Academic Article
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Vestigial-like 1 is a shared targetable cancer-placenta antigen expressed by pancreatic and basal-like breast cancers.
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Academic Article
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Applications of CRISPR Genome Editing to Advance the Next Generation of Adoptive Cell Therapies for Cancer.
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Academic Article
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Designed improvement to T-cell immunotherapy by multidimensional single cell profiling.
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Academic Article
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Randomized phase II trial of lymphodepletion plus adoptive cell transfer of tumor-infiltrating lymphocytes, with or without dendritic cell vaccination, in patients with metastatic melanoma.
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Academic Article
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Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade.
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Academic Article
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Efficacy, Safety, and Biomarker Analysis of Combined PD-L1 (Atezolizumab) and VEGF (Bevacizumab) Blockade in Advanced Malignant Peritoneal Mesothelioma.
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Academic Article
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LFA-1 activation enriches tumor-specific T cells in a cold tumor model and synergizes with CTLA-4 blockade.
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Academic Article
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Enhanced immune activation within the tumor microenvironment and circulation of female high-risk melanoma patients and improved survival with adjuvant CTLA4 blockade compared to males.
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Academic Article
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Charge-based interactions through peptide position 4 drive diversity of antigen presentation by human leukocyte antigen class I molecules.
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Academic Article
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Spatial PD-L1, immune-cell microenvironment, and genomic copy-number alteration patterns and drivers of invasive-disease transition in prospective oral precancer cohort.
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Academic Article
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Feasibility and Safety of Personalized, Multi-Target, Adoptive Cell Therapy (IMA101): First-in-Human Clinical Trial in Patients with Advanced Metastatic Cancer.
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